Needle-free mesotherapy is a non-invasive skin rejuvenation system. It is a method of delivering active substances to the deep layers of the skin to improve its condition, rejuvenate, reduce wrinkles, cellulite, stretch marks, flabbiness and discoloration. Needle-free mesotherapy uses the phenomenon of electroporation and electrophoresis. Electroporation consists in the impact of short pulses of electric voltage on cells and tissues, causing changes leading to increased skin permeability. It reaches the inside of the skin, which makes the therapy very effective. Electrophoresis is a physical phenomenon in which, during the transport of direct current, ionic substances are transferred through the skin. Both of these phenomena occur simultaneously, thanks to which it allows for a significant increase in the amount and depth of penetration of the applied active substances.